Sodium Cromoglicate Impurity 12 CAS CATO-C4X-201112
| CAS No. | CATO-C4X-201112 |
| Molecular Formula | C11H13ClO4 |
| Molecular Weight | 244.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Sodium Cromoglicate Impurity 12 (CAS CATO-C4X-201112, C11H13ClO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Sodium Cromoglicate Impurity 12 (C11H13ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Sodium Cromoglicate Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13ClO4 |
| Molecular Weight | 244.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Sodium Standards
- Sodium Cromoglicate Impurity C51 (CAS 16130-17-9)
- Sodium Cromoglicate Impurity 10 (CAS 50521-64-7)
- Sodium Cromoglicate Impurity 9 (CAS 3361-18-0)
- Sodium Cromoglicate Impurity 6 (CAS 802857-44-9)
- Sodium Cromoglicate Impurity 8 (CAS 16130-28-2)
- Sodium Cromoglicate Impurity 13 (CAS 53878-47-0)
- Cromoglicate EP Impurity A (CAS 699-83-2)
- Sodium Cromoglicate Impurity 30 (CAS CATO-C4X-201130)
Recommended Standards
- Diltiazem Impurity 31 (CAS CATO-C4X-136831)
- Nefopam Impurity 7 (CAS 22103-85-1)
- Isavuconazole Impurity 43 (CAS CATO-C4X-123643)
- 2-(4-Chlorophenyl)-1H-1,3-benzodiazol-1-ol (CAS 10066-08-7)
- Lenvatinib Impurity 37 (CAS CATO-C4X-114037)
- Pidotimod Impurity 7 (CAS CATO-C4X-10787)
- Tadalafil Impurity 86 HCl (CAS CATO-C4X-108786)
- 5-Methyl-3-nitro-2-propoxypyridine (CAS 1881296-70-3)
- tert-Butyl 4-(4-formyl-3-hydroxyphenyl)piperazine-1-carboxylate, 97% (CAS 1446332-69-9)
- (2S,4R)-4-Hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (CAS 1448297-55-9)
- 4-(Hydroxymethyl)-2,3-dimethylphenol (CAS 67730-45-4)
- Sulfadimethoxine EP Impurity C (CAS 121-62-0)
- 1-PIPERIDINEPROPIONIC ACID (CAS 26371-07-3)
- [Nva12]-Tirzepatide (CAS CATO-C4X-324042)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com