3-(difluoromethyl)cyclobutanecarboxylic acid CAS 1613330-49-6
| CAS No. | 1613330-49-6 |
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(difluoromethyl)cyclobutanecarboxylic acid.
3-(difluoromethyl)cyclobutanecarboxylic acid (CAS 1613330-49-6) is a high-purity analytical reference standard with the molecular formula C6H8F2O2 and a molecular weight of 150.12 g/mol.
Structurally, 3-(difluoromethyl)cyclobutanecarboxylic acid (C6H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 150.12 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(difluoromethyl)cyclobutanecarboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related difluoromethyl Standards
- 2-(Difluoromethyl)cyclobutane-1-carboxylic acid (CAS 1421601-68-4)
- 2-(difluoromethyl)furan-3-carbaldehyde (CAS 1706464-73-4)
- 1-(Difluoromethyl)cyclobutane-1-carboxylic acid (CAS 1773507-91-7)
- trans-3-(difluoromethyl)cyclobutanecarboxylic acid (CAS 1773508-02-3)
- 3-(Difluoromethyl)-5-methyl-4,5-dihydro-1H-pyrazol-5-ol (CAS 933768-35-5)
- 1-(Difluoromethyl)-1H-pyrazole-5-thiol (CAS 2923474-87-5)
- 2-(Difluoromethyl)thiazol-4-amine (CAS 930303-50-7)
- 3-(Difluoromethyl)isothiazol-5-amine (CAS 2270872-91-6)
Recommended Standards
- 3-Cyclopropyl-2,2-difluoropropanoic acid (CAS 1556048-70-4)
- 1-(2,2-Difluoroethyl)cyclopropane-1-carboxylic acid (CAS 1541125-74-9)
- Ethyl 2,2-difluorocyclopropanecarboxylate (CAS 151324-64-0)
- (1R,2R)-2-(difluoromethyl)cyclobutane-1-carboxylic acid (CAS 1773507-94-0)
- 2-(4-Fluoro-2-methylphenyl)-3-methylbutanoic acid (CAS 1249652-02-5)
- 4-Chloro-2-fluoro-5-nitrophenol (CAS 98404-02-5)
- 4-Propylpiperidin-3-one (CAS 944900-61-2)
- 3,3-Difluoro-3-(pyridin-4-yl)propanoic acid (CAS 1550969-62-4)
- 2-(4-(3-(2,6-Dichlorobenzyl)-2-methyl-4-oxopyridin-1(4H)-yl)phenyl)acetonitrile (CAS 478246-06-9)
- 3-Bromo-5-chloro-4-methoxybenzaldehyde (CAS 161565-36-2)
- Thiovardenafil (CAS 912576-24-0)
- 2-(Difluoromethyl)-6-hydroxy-3-methylpyridine-5-carboxylic acid (CAS 1806878-37-4)
- (1-Allyl-1H-pyrazol-4-yl)methanamine (CAS 1283702-25-9)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com