HTH-01-015, 99%, a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM) CAS 1613724-42-7

Description

The occurrence of HTH-01-015, 99%, a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM) is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

HTH-01-015, 99%, a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM) (CAS 1613724-42-7) is a high-purity analytical reference standard with the molecular formula C26H28N8O and a molecular weight of 468.55 g/mol.

The molecular framework of HTH-01-015, 99%, a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM) (C26H28N8O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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