Mivacurium Chloride Impurity 12 CAS 161816-38-2
| CAS No. | 161816-38-2 |
| Molecular Formula | C33H46NO9 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Mivacurium Chloride Impurity 12 (CAS 161816-38-2, C33H46NO9Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mivacurium Chloride Impurity 12 (C33H46NO9Cl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H46NO9 Cl |
| Molecular Weight | 636.18 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Mivacurium Standards
- Mivacurium Chloride Impurity 5 (CAS 1026602-92-5)
- Mivacurium Chloride Impurity 21 (CAS 104758-47-6)
- Mivacurium chloride Impurity 25 (CAS 104758-49-8（free base）)
- Mivacurium Chloride Impurity 7 (S-S isomer) (CAS 104758-51-2)
- Mivacurium (CAS 106791-40-6)
- Mivacurium Chloride (Mixture of Diastereomers) (CAS 106861-44-3)
- Mivacurium Chloride Impurity 6 (R-S isomer) (CAS 107740-63-6)
- Mivacurium Chloride Impurity 14 (CAS 107740-64-7)
Recommended Standards
- Apixaban Impurity 61 (CAS CATO-C4X-108861)
- Pretomanid Impurity 21 (CAS CATO-C4X-260621)
- Haloperidol Impurity 39 (CAS 52669-92-8)
- N-(5,6-dihydrobenzo[h]quinazolin-2-yl)-2-(isopropylthio)acetamide (CAS 338959-72-1)
- N-(3,4-dimethylphenyl)-2-((5-(4-ethoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 868255-50-9)
- 1-(Bromomethyl)-4-(1,1,2,2-tetrafluoroethoxy)benzene (CAS 67033-41-4)
- n-(1,3-Dioxaindan-5-yl)-2-{[5-(1h-indol-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide (CAS 380451-75-2)
- Isopropyl 1h-indole-3-carboxylate (CAS 61698-92-8)
- 2-Fluoro-1-methoxy-4-methoxymethoxybenzene (CAS 133788-99-5)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
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