Apixaban Impurity 34 CAS 1619934-76-7
| CAS No. | 1619934-76-7 |
| Molecular Formula | C31H37N5O6 |
| Molecular Weight | 575.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apixaban Impurity 34 (C31H37N5O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Apixaban Impurity 34 (CAS 1619934-76-7) is a certified pharmaceutical impurity reference standard with the molecular formula C31H37N5O6 and a molecular weight of 575.66 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H37N5O6 |
| Molecular Weight | 575.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 160 (CAS CATO-C4X-1088160)
- Apixaban USP Related Compound G (CAS 881386-12-5)
- Apixaban Impurity 24 (CAS 1998079-16-5)
- Apixaban Impurity 66 (CAS CATO-C4X-108866)
- Apixaban Impurity 71 (CAS 1998079-15-4)
- Apixaban Impurity 179 (CAS CATO-C4X-1088179)
- Apixaban Impurity 144 (CAS CATO-C4X-1088144)
- Apixaban Impurity 69 (CAS CATO-C4X-108869)
Recommended Standards
- N-(2-((2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)thio)ethyl)-5-(dimethylamino)naphthalene-1-sulfonamide (CAS 75501-09-6)
- H-Pro-Phe-Arg-AMC (CAS 65147-21-9)
- 2-(2,7-Bis(N-(o-tolyl)sulfamoyl)-9H-fluoren-9-ylidene)hydrazinecarboxamide (CAS 303059-57-6)
- Zafirlukast m-Tolyl Isomer (CAS 1159195-69-3)
- Cefoxitin Impurity 16 (CAS CATO-C4X-157816)
- Blonanserin Impurity 40 (CAS 1477480-40-2)
- Coclaurine Impurity 112 (CAS 116331-72-7)
- 5-(2-methyl-5-propyl-1,3-thiazol-4-yl)-1,3,4-oxadiazol-2-amine (CAS 950272-29-4)
- N-(3,4-dimethoxybenzyl)-2-(5-methoxy-1H-indol-3-yl)ethan-1-amine (CAS 289476-17-1)
- 5-Chloro-3-(thiophen-2-ylmethyl)-1,2,4-thiadiazole (CAS 1338218-71-5)
- 339286-30-5 6-Chloro-5-nitro-2-(propylsulfanyl)pyrimidin-4-amine DTXSID80855777 (CAS 339286-30-5)
- 2,2'-(Cyclohexane-1,1-diyl)bis(ethan-1-ol) (CAS 3187-27-7)
- 4-(Bromomethyl)-5-(chloromethyl)-1,3-dioxol-2-one (CAS 209551-70-2)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
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