Apixaban Impurity 160 CAS CATO-C4X-1088160
| CAS No. | CATO-C4X-1088160 |
| Molecular Formula | C30H34ClN5O5 |
| Molecular Weight | 580.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Apixaban Impurity 160 (C30H34ClN5O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Apixaban Impurity 160 (CAS CATO-C4X-1088160), a pharmacopoeial impurity reference standard (molecular formula C30H34ClN5O5, MW 580.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apixaban Impurity 160 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H34ClN5O5 |
| Molecular Weight | 580.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 34 (CAS 1619934-76-7)
- Apixaban USP Related Compound G (CAS 881386-12-5)
- Apixaban Impurity 24 (CAS 1998079-16-5)
- Apixaban Impurity 66 (CAS CATO-C4X-108866)
- Apixaban Impurity 71 (CAS 1998079-15-4)
- Apixaban Impurity 179 (CAS CATO-C4X-1088179)
- Apixaban Impurity 144 (CAS CATO-C4X-1088144)
- Apixaban Impurity 128 (CAS CATO-C4X-1088128)
Recommended Standards
- Perfluoro-1,4,7,10,13-pentaoxacyclopentadecane (CAS 97571-69-2)
- Tolvaptan Impurity 44 (CAS 2458812-61-6)
- Edoxaban Impurity 97 (Mixture of Diastereomers) (CAS CATO-C4X-106397)
- 4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-yl)phenyl benzoate (CAS 867331-82-6)
- Betacarotene EP Impurity C (CAS CATO-C4X-28153)
- Lusutrombopag Impurity N4 (CAS 1110767-98-0)
- Alectinib Impurity 73 (CAS CATO-C4X-283673)
- 4-Ethyl-2-nitrobenzoic acid (CAS 141030-64-0)
- 2-(Chloromethyl)-5-(difluoromethyl)-4-hydroxy-3-nitropyridine (CAS 1805204-00-5)
- 6-Bromo-7-fluoro-3,4-dihydro-2H-1,4-benzoxazine, 97% (CAS 1160102-28-2)
- Methyl 4-[(4-piperidinyloxy)methyl]benzoatehydrochloride (CAS 1220034-19-4)
- Cesium orthovanadate (CAS 34283-69-7)
- 4-Bromo-2-cyano-6-(difluoromethyl)benzoic acid (CAS 1807116-11-5)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com