1, 3, 5(10)-ESTRATRIEN-2-FLUORO-3, 17β-DIOL CAS 16205-32-6
| CAS No. | 16205-32-6 |
| Molecular Formula | C18H23FO2 |
| Molecular Weight | 290.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1, 3, 5(10)-ESTRATRIEN-2-FLUORO-3, 17β-DIOL.
CATO supplies 1, 3, 5(10)-ESTRATRIEN-2-FLUORO-3, 17β-DIOL (CAS 16205-32-6), a certified reference material (molecular formula C18H23FO2, MW 290.37 g/mol) for analytical method development and quality control.
The molecular framework of 1, 3, 5(10)-ESTRATRIEN-2-FLUORO-3, 17β-DIOL (C18H23FO2) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23FO2 |
| Molecular Weight | 290.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F-containing |
Related ESTRATRIEN Standards
- 1, 3, 5(10)-ESTRATRIEN-3, 15α, 17β-TRIOL (CAS 570-30-9)
- 1, 3, 5(10)-ESTRATRIEN-3, 15β, 17β-TRIOL (CAS 7445-96-7)
- 1, 3, 5(10)-ESTRATRIEN-17α-METHYL-3, 17β-DIOL (CAS 302-76-1)
- 1, 3, 5(10)-ESTRATRIEN-2, 3, 17β-TRIOL 3-METHYL ETHER (CAS 1236-72-2)
- 1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 17-PROPIONATE (CAS 3758-34-7)
- 1,3,5(10)-Estratrien-2,3,4,17beta-tetrol-2,4-dimethyl Ether (CAS 65968-99-2)
- 1, 3, 5(10)-ESTRATRIEN-3-16α-DIOL-17-ONE DIACETATE (CAS 1247-70-7)
- 1,3,5(10)-Estratrien-3-ol-17-one hemisuccinate 4-((8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy)-4-oxobutanoic acid 58534-72-8 (CAS 58534-72-8)
Recommended Standards
- 1-Bromo-2-(trichloromethoxy)benzene (CAS 1404194-61-1)
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- 1-Bromo-3-(trichloromethoxy)benzene (CAS 1404193-84-5)
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- 5-(Benzyloxy)-1H-indazole-3-carboxylic acid (CAS 177941-16-1)
- 2-(Dimethylamino)-2-(p-tolyl)acetonitrile (CAS 15229-65-9)
- 4-Chloro-5-fluoro-3-methyl-1H-indazole (CAS 1956379-09-1)
- (R)-4-((4,5-Dihydro-1H-imidazol-2-yl)(hydroxy)methyl)benzene-1,2-diol (CAS 85232-94-6)
- 4-Amino-2-(difluoromethyl)nicotinonitrile (CAS 1805254-37-8)
- N-Methyl-6-phenylimidazo[1,2-a]pyrazin-8-amine (CAS 787591-86-0)
- Minoxidil Impurity 57 (CAS CATO-C4X-170057)
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- 4-(3-Fluoro-5-nitrophenyl)-2,6-dimethylmorpholine (CAS 1502603-37-3)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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