| CAS No. | 3758-34-7 |
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of 1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 17-PROPIONATE is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 17-PROPIONATE (CAS 3758-34-7), molecular formula C21H28O3 and molecular weight 328.45 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 17-PROPIONATE (C21H28O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 328.45 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 17-PROPIONATE meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |