3-(2-Bromophenyl)-2H-chromen-2-one CAS 1620681-03-9
| CAS No. | 1620681-03-9 |
| Molecular Formula | C15H9BrO2 |
| Molecular Weight | 301.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Bromophenyl)-2H-chromen-2-one (CAS 1620681-03-9), molecular formula C15H9BrO2 and molecular weight 301.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-Bromophenyl)-2H-chromen-2-one (C15H9BrO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Bromophenyl)-2H-chromen-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9BrO2 |
| Molecular Weight | 301.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
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Recommended Standards
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- 3-(4-Bromo-phenyl)coumarin (CAS 16807-64-0)
- Ethyl (2E)-2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-3-[(4-methoxyphenyl)amino]prop-2-enoate (CAS 338422-78-9)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine (CAS 2765268-27-5)
- 3-Phenylcyclobutan-1-amine hydrochloride (CAS 90874-40-1)
- 5,7-Dibromo-2-methyl-4H-benzo[d][1,3]oxazin-4-one (CAS 76443-44-2)
- Tetrahydro-N-methyl-2H-pyran-4-ethanamine (CAS 1083216-46-9)
- 2-(Chloromethyl)-5-(methylsulfonyl)pyridine (CAS 1196151-88-8)
- 4-[4-(Trifluoromethoxy)phenyl]pyrimidine-2-carboxylic Acid (CAS 912850-80-7)
- N-(5-Methyl-4,5-dihydrooxazol-2-yl)benzamide (CAS 802321-46-6)
- 5-Iodo-1h-indole-2-carboxylic acid (CAS 99066-64-5)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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