4-[4-(Trifluoromethoxy)phenyl]pyrimidine-2-carboxylic Acid CAS 912850-80-7
| CAS No. | 912850-80-7 |
| Molecular Formula | C12H7F3N2O3 |
| Molecular Weight | 284.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-[4-(Trifluoromethoxy)phenyl]pyrimidine-2-carboxylic Acid (C12H7F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 284.19 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-[4-(Trifluoromethoxy)phenyl]pyrimidine-2-carboxylic Acid (CAS 912850-80-7) is a high-purity analytical reference standard with the molecular formula C12H7F3N2O3 and a molecular weight of 284.19 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[4-(Trifluoromethoxy)phenyl]pyrimidine-2-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7F3N2O3 |
| Molecular Weight | 284.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethoxy Standards
- 6-[4-(Trifluoromethoxy)phenyl]pyrazine-2-carboxylic Acid (CAS 1258269-13-4)
- 2-(2-(Trifluoromethoxy)phenyl)pyrimidine-5-carboxylic acid (CAS 1261765-94-9)
- 2-[4-(Trifluoromethoxy)phenyl]pyrimidine-4-carboxylic Acid (CAS 1864059-55-1)
- 2-{5-Oxo-4-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetonitrile (CAS 866149-42-0)
- 2-((4-(Trifluoromethoxy)phenyl)sulfonyl)acetic acid (CAS 773098-22-9)
- 6-(4-methyl-3-(trifluoromethoxy)phenoxy)pyridin-3-amine (CAS 1311138-98-3)
- (4-(4-(Trifluoromethoxy)phenoxy)phenyl)methanol (CAS 1686102-84-0)
- 2-(trifluoromethoxy)ethyl 4-methylbenzenesulfonate (CAS 1897449-20-5)
Recommended Standards
- 4-[(4-Bromo-2-methylphenoxy)methyl]piperidine (CAS 946714-05-2)
- 4-Bromo-N,N-diisopropylbenzamide (CAS 79606-46-5)
- 4-[(2-Bromo-4-methylphenoxy)methyl]piperidine (CAS 946725-26-4)
- 4-Bromo-N-hexylbenzamide (CAS 346688-97-9)
- Cyclazosin hydrochloride (CAS 146929-33-1)
- N-(4-Benzyl-2-methyloxazol-5-yl)-2,2,2-trifluoroacetamide (CAS 87784-06-3)
- Microcystin-RR (CAS 111755-37-4)
- Daprodustat impurity 6 (CAS CATO-C4X-24076)
- N,2,6-trimethylcyclohexan-1-amine hydrochloride (CAS 1269152-63-7)
- 898755-91-4 1-[3,5-Bis(trifluoromethyl)phenyl]-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one DTXSID00646008 (CAS 898755-91-4)
- 4-(3-Phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid (CAS 26192-69-8)
- 4-(4-(Oxetan-3-yl)piperazin-1-yl)aniline (CAS 1395030-33-7)
- 4-{6-[(2-Pyridinylmethyl)amino]-1H-pyrrolo[2,3-b]pyridin-4-yl}benzoic acid (CAS 1377872-06-4)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
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