Vilazodone impurity 1 CAS 1622425-52-8
| CAS No. | 1622425-52-8 |
| Molecular Formula | C26H27N5O3 |
| Molecular Weight | 457.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Vilazodone impurity 1 (C26H27N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 457.52 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Vilazodone impurity 1 (CAS 1622425-52-8) is a certified pharmaceutical impurity reference standard with the molecular formula C26H27N5O3 and a molecular weight of 457.52 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vilazodone impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H27N5O3 |
| Molecular Weight | 457.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 5 |
Related Vilazodone Standards
- Vilazodone Impurity 19 (CAS 1588795-58-7)
- Vilazodone-d8 (CAS 1794789-93-7)
- Vilazodone Ethyl Ester hydrochloride (CAS 1422956-25-9)
- Vilazodone impurity 02 (CAS 163521-11-7)
- Vilazodone impurity 01 (CAS 163521-19-5)
- Vilazodone (CAS 163521-12-8)
- Vilazodone impurity 15 (CAS 2970582-50-2)
- Vilazodone impurity 16 (CAS 795266-89-6)
Recommended Standards
- Azilsartan Impurity 113 (CAS 177965-03-6)
- Indobufen Impurity 20 (CAS CATO-C4X-179220)
- Dronedarone Impurity 43 (CAS CATO-C4X-109243)
- Irbesartan Impurity 15 (CAS CATO-C4X-166615)
- Benzhexol Impurity 11 (CAS 161564-79-0)
- Crizotinib impurity 13 (CAS CATO-C4X-102513)
- Suvorexant impurity 28 (CAS CATO-C4X-181228)
- 2-Tributylstannylbenzo[b]furan (CAS 148961-81-3)
- Ethyl 1-(6-methoxypyridin-2-yl)piperidine-4-carboxylate (CAS 1241894-57-4)
- 1-Cyclopentylcyclohexane-1-carboxylic acid (CAS 78343-35-8)
- 1-(5-Bromo-2-methoxybenzyl)piperidin-3-ol (CAS 414872-73-4)
- 5-Isopropyl-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 1513605-88-3)
- Benzofuran-5-yl-oxoacetic acid ethyl ester (CAS 79002-37-2)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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