Indobufen Impurity 20 CAS CATO-C4X-179220
| CAS No. | CATO-C4X-179220 |
| Molecular Formula | C28H27NO5 |
| Molecular Weight | 457.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Indobufen Impurity 20 (CAS CATO-C4X-179220) is a certified pharmaceutical impurity reference standard with the molecular formula C28H27NO5 and a molecular weight of 457.52 g/mol.
The molecular framework of Indobufen Impurity 20 (C28H27NO5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C28H27NO5 |
| Molecular Weight | 457.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Indobufen Standards
- Indobufen Impurity 63 (CAS CATO-C4X-179263)
- Indobufen Impurity 67 (CAS CATO-C4X-179267)
- Indobufen Impurity 65 (CAS CATO-C4X-179265)
- Indobufen Impurity 62 (CAS CATO-C4X-179262)
- Indobufen Impurity 72 (CAS CATO-C4X-179272)
- Indobufen Impurity 56 (CAS 858847-37-7)
- Indobufen Impurity 60 (CAS CATO-C4X-179260)
- Indobufen Impurity 66 (CAS CATO-C4X-179266)
Recommended Standards
- Vilazodone impurity 1 (CAS 1622425-52-8)
- Irbesartan Impurity 15 (CAS CATO-C4X-166615)
- Azilsartan Impurity 113 (CAS 177965-03-6)
- Irbesartan Impurity 16 (CAS CATO-C4X-166616)
- Mirtazapine EP Impurity B (CAS 61337-89-1)
- Amorolfine Impurity 52 (CAS CATO-C4X-154252)
- Rivaroxaban Impurity 121 (CAS 1855920-51-2)
- (1S,2S)-Cyclohex-4-ene-1,2-diamine (CAS 1241684-26-3)
- 4-Phenyl-1,2,3-thiadiazole-5-carboxylic acid (CAS 78875-63-5)
- n-((5-Sulfamoylthiophen-2-yl)methyl)propionamide (CAS 1099052-73-9)
- (S)-cyclopropyl(pyridin-3-yl)methanamine (CAS 1213680-69-3)
- Ethyl 6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate (CAS 6633-65-4)
- Tert-butyl (5-chloro-2-nitrophenyl)carbamate (CAS 388571-30-0)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
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