Nintedanib-D3 CAS 1624587-84-3
| CAS No. | 1624587-84-3 |
| Molecular Formula | - |
| Molecular Weight | 542.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Nintedanib-D3 (C31H30D3N5O4) is characterized by deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Nintedanib-D3 (CAS 1624587-84-3), molecular formula C31H30D3N5O4 and molecular weight 542.64 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H30D3N5O4 |
| Molecular Weight | 542.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 5 |
Related Nintedanib Standards
- Nintedanib-13C-d3 (Intedanib-13C-d3) (CAS CATO-C4X-181454)
- Nintedanib E-Isomer (CAS 1160294-26-7)
- Nintedanib (CAS 656247-17-5)
- Nintedanib Impurity 23 (CAS CATO-C4X-181423)
- (E)-Nintedanib (CAS CATO-C4X-181450)
- Nintedanib-d8 (CAS 1624587-87-6)
- Nintedanib Impurity 105 (CAS CATO-C4X-1814105)
- Nintedanib Impurity 101 (CAS CATO-C4X-1814101)
Recommended Standards
- 2-3-4-6-Tetra-O-benzyl-D-glucopyranosyl fluoride (CAS 122741-44-0)
- (2R,3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-fluorotetrahydro-2H-pyran (CAS 94898-42-7)
- Z-Phe-Tyr(tBu)-diazomethylketone (CAS 114014-15-2)
- 2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl fluoride (CAS 78153-79-4)
- N-(6-Methyl-4-oxo-1,4-dihydroquinazolin-2-yl)benzamide (CAS 94066-18-9)
- 9α-Bromo Flunisolide (CAS CATO-C4X-16483)
- 2-Isopropylazetidine (CAS 777888-12-7)
- 3-(5-Methylisoxazol-3-yl)benzonitrile (CAS 1231244-50-0)
- 3-(2,4-Dimethoxyphenyl)-N-(1-phenylethyl)acrylamide (CAS 496779-83-0)
- 3-Hydroxythiophene-2-carboxamide (CAS 57059-24-2)
- 4-Chloro-3-((pyridin-2-yloxy)methyl)aniline (CAS 642084-80-8)
- 1-tert-Butyl 3-ethyl 2-(6-nitropyridin-3-yl)malonate (CAS 1333509-17-3)
- 2-(5-Methoxy-1H-benzo[d]imidazol-2-yl)-N-methylethanamine hydrochloride (CAS 1392207-91-8)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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