8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline-2,4(1H,3H)-dione CAS 1626337-88-9
| CAS No. | 1626337-88-9 |
| Molecular Formula | C14H17BN2O4 |
| Molecular Weight | 288.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline-2,4(1H,3H)-dione.
CATO supplies 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline-2,4(1H,3H)-dione (CAS 1626337-88-9), a certified reference material (molecular formula C14H17BN2O4, MW 288.11 g/mol) for analytical method development and quality control.
8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline-2,4(1H,3H)-dione (C14H17BN2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17BN2O4 |
| Molecular Weight | 288.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Tetramethyl Standards
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazoline-2,4(1H,3H)-dione (CAS 1209498-42-9)
- 5-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)-1,3,4-oxadiazol-2-amine (CAS 1272357-34-2)
- (E)-6-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)oxazolo[4,5-b]pyridin-2(3H)-one (CAS 2377227-47-7)
- 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran-2-carboxylic acid (CAS 2377609-29-3)
- N-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)cyclopropanecarboxamide (CAS 1201644-35-0)
- 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)pyrrolidin-2-one (CAS 1201644-51-0)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carboxylic acid (CAS 1218790-98-7)
- N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)cyclopropanecarboxamide (CAS 1286230-87-2)
Recommended Standards
- 2-iodo-5-phenyl-1,3,4-thiadiazole (CAS 1461714-16-8)
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- 4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenylboronic Acid Pinacol Ester (CAS 1454814-36-8)
- (4-(Dibenzo[b,d]furan-4-yl)phenyl)boronic acid (CAS 796071-96-0)
- 4-Chloro-3-(methanesulfonylmethyl)aniline (CAS 1178024-93-5)
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- N-(3-chloro-2-methylphenyl)-6-methylimidazo[2,1-b]thiazole-5-carboxamide (CAS 478066-28-3)
- 5-Hydroxy-4-(4-methoxyphenyl)isoquinolin-1(2H)-one (CAS 656234-25-2)
- Avibactam Impurity 132 (CAS CATO-C4X-1348132)
- 4,5-Difluoro-2-(perfluoroethyl)-1,3-dioxole (CAS 150622-65-4)
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- 1-(4-(Cyclohexyloxy)phenyl)-1H-imidazole (CAS 502656-64-6)
- Ethyl (1S,3S,4S)-4-amino-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate (CAS 2231664-17-6)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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