2,5-Bis(3,5-difluorophenyl)pyridine CAS 1627313-24-9
| CAS No. | 1627313-24-9 |
| Molecular Formula | C17H9F4N |
| Molecular Weight | 303.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,5-Bis(3,5-difluorophenyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2,5-Bis(3,5-difluorophenyl)pyridine (CAS 1627313-24-9), a certified reference material (molecular formula C17H9F4N, MW 303.25 g/mol) for analytical method development and quality control.
The molecular framework of 2,5-Bis(3,5-difluorophenyl)pyridine (C17H9F4N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,5-Bis(3,5-difluorophenyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H9F4N |
| Molecular Weight | 303.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 6-(3,4-Difluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one (CAS 1923082-71-6)
- (2,6-Difluorophenyl)(2-phenylmorpholino)methanone (CAS 954066-12-7)
- (3,4-Difluorophenyl)(2-phenylmorpholino)methanone (CAS 920153-34-0)
- 1-[(2,4-Difluorophenyl)(phenyl)methyl]-1,4-diazepane (CAS 507220-04-4)
- N-(3,4-Difluorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142207-31-5)
- 4-((3,5-Difluorophenyl)amino)-6-(pyrrolidin-1-yl)-1,3,5-triazine-2-carbonitrile (CAS 1311279-71-6)
- 2-(3,5-Difluorophenyl)-7-methoxy-8-methylquinazolin-4(3H)-one (CAS 922520-31-8)
- N4-(3,4-Difluorophenyl)-7-methoxyquinazoline-4,6-diamine (Dacomitinib Impurity) (CAS 2117703-26-9)
Recommended Standards
- Ethyl 3-[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]-1,2,4-oxadiazole-5-carboxylate (CAS 1338651-59-4)
- 2-(4-MEthanesulfonyl-2-nitrophenyl)propanedioic acid (CAS 773869-70-8)
- N,2-Dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]propan-2-amine (CAS 1310835-41-6)
- 2-(n-(Carboxymethyl)sulfamoyl)terephthalic acid (CAS 741731-78-2)
- Methyl 3-(tert-butyl)-5-iodobenzoate (CAS 217476-42-1)
- 4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline (CAS 217480-50-7)
- 2-[(2-chlorophenyl)methoxy]benzohydrazide (CAS 379255-59-1)
- tert-Butyl (1-carbamoylcyclopropyl)carbamate (CAS 507264-66-6)
- 1-(2-Fluorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-72-9)
- 5-Isopropyl-1,3,5-dithiazinane (CAS 34866-41-6)
- (1-Methyl-1H-imidazol-5-yl)methyl 4-chlorobenzoate (CAS 866131-15-9)
- 4-((3-Formylpyridin-2-yl)oxy)benzonitrile (CAS 866049-85-6)
- 1-[1-(Methoxymethyl)-1H-1,2,4-triazol-5-yl]piperazine (CAS 1630763-45-9)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
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