6-(3,4-Difluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one CAS 1923082-71-6
| CAS No. | 1923082-71-6 |
| Molecular Formula | C16H11F2NO3 |
| Molecular Weight | 303.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(3,4-Difluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one (C16H11F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 6-(3,4-Difluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one (CAS 1923082-71-6), a certified reference material (molecular formula C16H11F2NO3, MW 303.26 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(3,4-Difluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11F2NO3 |
| Molecular Weight | 303.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
- 2,5-Bis(3,5-difluorophenyl)pyridine (CAS 1627313-24-9)
- (2,6-Difluorophenyl)(2-phenylmorpholino)methanone (CAS 954066-12-7)
- (3,4-Difluorophenyl)(2-phenylmorpholino)methanone (CAS 920153-34-0)
- 1-[(2,4-Difluorophenyl)(phenyl)methyl]-1,4-diazepane (CAS 507220-04-4)
- N-(3,4-Difluorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142207-31-5)
- 4-((3,5-Difluorophenyl)amino)-6-(pyrrolidin-1-yl)-1,3,5-triazine-2-carbonitrile (CAS 1311279-71-6)
- 2-(3,5-Difluorophenyl)-7-methoxy-8-methylquinazolin-4(3H)-one (CAS 922520-31-8)
- N4-(3,4-Difluorophenyl)-7-methoxyquinazoline-4,6-diamine (Dacomitinib Impurity) (CAS 2117703-26-9)
Recommended Standards
- 4-Methyl-2-(4-(trifluoromethoxy)phenyl)thiazole-5-carboxylic acid (CAS 187998-69-2)
- 2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(2,4,5-trifluorophenyl)acetamide (CAS 868256-07-9)
- AZD3759-25 (CAS 184475-78-3)
- 2-(Benzenesulfonyl)-5-(trifluoromethyl)pyridin-3-ol (CAS 338956-57-3)
- (Z)-Ethyl 2-azido-3-(3-fluoro-4-methoxyphenyl)acrylate (CAS 136818-63-8)
- 4-(Aminomethyl)-5-cyano-2-methylbenzene-1-sulfonyl chloride (CAS 1805964-28-6)
- 1-(Benzo[d]thiazol-5-yl)ethanamine (CAS 916201-66-6)
- 67746-43-4 Bis(benzyloxy)(diethylamino)phosphine Dibenzyl (Diethylamido)phosphite Dibenzyl N,N-Diethylphosphoramidite, Technical Grade inverted exclamation markY85% Dibenzyl N,N-diethylphosphoramidite Dibenzyloxydiethylaminophosphine N,N-Diethyl-phosphoramidous Acid Bis(phenylmethyl) Ester TTC (CAS 67746-43-4)
- 4-(Sulfamoylamino)phenylboronic Acid (CAS 1298033-59-6)
- 3-(Adamantan-1-yl)-4'-bromobiphenyl-4-ol (CAS 496868-80-5)
- Umeclidinium bromide Impurity 21 (CAS 40117-63-3)
- 4-(3-(Trifluoromethyl)pyridin-2-yl)-N-(5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxamide (CAS 821768-06-3)
- Ethyl 2-(2-chloroacetamido)-5-(cyanosulfanyl)-4-phenylthiophene-3-carboxylate (CAS 726151-90-2)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com