Docetaxel EP Impurity D CAS 162784-72-7
| CAS No. | 162784-72-7 |
| Molecular Formula | C43H51NO14 |
| Molecular Weight | 805.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Docetaxel EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Docetaxel EP Impurity D (CAS 162784-72-7) is a certified pharmaceutical impurity reference standard with the molecular formula C43H51NO14 and a molecular weight of 805.86 g/mol.
The molecular framework of Docetaxel EP Impurity D (C43H51NO14) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C43H51NO14 |
| Molecular Weight | 805.86 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
Related Docetaxel Standards
- Docetaxel EP Impurity B (CAS 167074-97-7)
- Docetaxel Impurity 8 (CAS CATO-C4X-16198)
- Docetaxel EP Impurity B (CAS CATO-C4X-161980)
- Docetaxel (Anhydrous) (CAS 114977-28-5)
- Docetaxel EP Impurity C (CAS 153381-68-1)
- Docetaxel Impurity 49 (CAS 1095547-86-6)
- Docetaxel Impurity 62 (CAS CATO-C4X-161962)
- Docetaxel Impurity 77 (CAS CATO-C4X-161977)
Recommended Standards
- 6,7-Epoxy Docetaxel(Mixture of Diastereomers) (CAS 181208-36-6)
- Penimocycline (CAS 16259-34-0)
- Ac-Leu-Asp-Gln-Trp-Phe-Gly-NH2 (CAS 129809-09-2)
- Evonimine (CAS 41758-69-4)
- Milrinone Impurity 21 (CAS 2497745-31-8)
- Omeprazole EP Impurity B (CAS 110374-16-8)
- Edoxaban Impurity 120 Iodide (CAS CATO-C4X-1063120)
- 4-Allyl-1-benzylpiperidin-4-ol (CAS 883291-28-9)
- 5-Bromo-N,N-diethylpyrazin-2-amine (CAS 959238-87-0)
- N-Acetyl Dapsone (CAS 565-20-8)
- N,N-Diphenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 915088-14-1)
- 3,5-Dimethylpiperidine-1-sulfonyl chloride (CAS 923249-49-4)
- 2-Chloro-1-naphthaldehyde (CAS 25986-40-7)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
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