Palbociclib-d8 CAS 1628752-83-9
| CAS No. | 1628752-83-9 |
| Molecular Formula | - |
| Molecular Weight | 455.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Palbociclib-d8 (CAS 1628752-83-9) is a high-purity analytical reference standard with the molecular formula C24H21D8N7O2 and a molecular weight of 455.58 g/mol.
Palbociclib-d8 (C24H21D8N7O2) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H21D8N7O2 |
| Molecular Weight | 455.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib-D4 (CAS 1628752-63-5)
- Palbociclib Impurity 127 (CAS CATO-C4X-1125127)
- Palbociclib impurity 163 (CAS CATO-C4X-1125163)
- Palbociclib Impurity 147 (CAS 2624141-94-0)
- Palbociclib Impurity 56 (CAS 571189-51-0)
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- Palbociclib Impurity 189 (CAS CATO-C4X-1125189)
- Palbociclib Impurity 186 (CAS 2174002-29-8)
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