Palbociclib Impurity 22 CAS 1376615-91-6
| CAS No. | 1376615-91-6 |
| Molecular Formula | C24H31N7O2 |
| Molecular Weight | 449.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Palbociclib Impurity 22 (CAS 1376615-91-6) is a certified pharmaceutical impurity reference standard with the molecular formula C24H31N7O2 and a molecular weight of 449.55 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Palbociclib Impurity 22 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 449.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Palbociclib Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H31N7O2 |
| Molecular Weight | 449.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib Impurity 7 (CAS CATO-C3D-1456)
- Palbociclib Impurity 41 (CAS CATO-C4X-112541)
- Palbociclib Impurity N87 (CAS 2205035-04-5)
- Palbociclib (CAS 571190-30-2)
- Palbociclib Impurity 11 (CAS CATO-C4X-112511)
- Palbociclib Impurity 157 (CAS CATO-C4X-1125157)
- Palbociclib Impurity 159 (CAS 2204368-66-9)
- Palbociclib Impurity 20 (CAS CATO-C3D-1542)
Recommended Standards
- Valsartan Impurity 93 (CAS CATO-C4X-105793)
- (S)-5-(tert-Butyl)-3-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-2,3-dihydro-1,3,4-thiadiazole-2-carboxylic acid (CAS 109683-61-6)
- Valsartan Impurity 83 (CAS CATO-C4X-105783)
- Azido-PEG3-S-PEG4-propargyl (CAS 2055041-24-0)
- Clofazimine Impurity N2 (CAS 24396-82-5)
- Eplerenone Impurity 37 (CAS CATO-C4X-163037)
- Rivaroxaban Impurity 124 (CAS CATO-C4X-1090124)
- Boc-Nle-OSu (CAS 36360-61-9)
- Tert-butyl 4-cyano-3,3-difluoropyrrolidine-1-carboxylate (CAS 1781329-92-7)
- (S)-1-(4-Chloropyridin-2-yl)but-3-en-1-amine (CAS 1270210-49-5)
- Amino-PEG4-C1-Boc (CAS 864680-64-8)
- Methyl 5-(difluoromethyl)-3-hydroxythiophene-2-carboxylate (CAS 181313-01-9)
- 1-Acetyl-3-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 5236-78-2)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com