4,4'-Difluoro-[1,1'-biphenyl]-3,3',5,5'-tetracarboxylic acid CAS 1628901-94-9
| CAS No. | 1628901-94-9 |
| Molecular Formula | C16H8F2O8 |
| Molecular Weight | 366.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 366.23 g/mol gives 4,4'-Difluoro-[1,1'-biphenyl]-3,3',5,5'-tetracarboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4,4'-Difluoro-[1,1'-biphenyl]-3,3',5,5'-tetracarboxylic acid (CAS 1628901-94-9), molecular formula C16H8F2O8 and molecular weight 366.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4,4'-Difluoro-[1,1'-biphenyl]-3,3',5,5'-tetracarboxylic acid (C16H8F2O8) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4,4'-Difluoro-[1,1'-biphenyl]-3,3',5,5'-tetracarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8F2O8 |
| Molecular Weight | 366.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 5,6-Difluoro-4-(methoxymethoxy)-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2883770-87-2)
- 5,8-Difluoro-3,3,4,4-tetramethyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918645-76-8)
- 2,5-Difluoro-1,4-Benzenediboronic Acid Bis(pinacol) Ester (CAS 303006-90-8)
- 1,3-Difluoro-2,4-diiodo-benzene (CAS 1208074-68-3)
- 1,2-Difluoro-3,4-diiodobenzene (CAS 933672-12-9)
- 1,2-Difluoro-4,5-diiodobenzene (CAS 210567-10-5)
- 1,4-Difluoro-2,3-diiodobenzene (CAS 501432-99-1)
- 2,3-Difluoro-1,4-diiodobenzene (CAS 501433-06-3)
Recommended Standards
- 3-(6-(4-Bromophenyl)-5-methylthiazolo[3,2-b][1,2,4]triazol-2-yl)propanoic acid (CAS 1437482-01-3)
- (2E)-3-(6-Bromo-2H-1,3-benzodioxol-5-yl)-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 478064-52-7)
- 2-(2-Fluoro-4-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1248556-35-5)
- 1-[3,5-Bis(trifluoromethyl)phenyl]-3-(4-fluorophenyl)urea (CAS 978-65-4)
- 4-(3-(2-Aminoethyl)ureido)-N-methyl-N-(1,1,4,4,5,5,8,8-octamethyl-1,2,3,4,5,6,7,8-octahydroanthracen-9-yl)benzamide (CAS CATO-C3D-262695)
- N-(2-phenylpropyl)hexan-2-amine (CAS 1157675-40-5)
- N-(2-Aminoethyl)-2-(4-methoxyphenyl)acetamide (CAS 53673-37-3)
- 5H-Pyrrolo[2,3-b]pyrazine (CAS 4745-93-1)
- 5-Cyclopropoxy-4-ethylnicotinaldehyde (CAS 1243357-29-0)
- 4-Hydroxy-1-[2-(trifluoromethyl)phenyl]-1h-pyrazole-3-carboxylic acid (CAS 956203-24-0)
- 7,7′-Dibromo-9,9,9′,9′-tetraoctyl-2,2′-bi-9H-fluorene (CAS 428865-53-6)
- tert-Butyl (R)-2-Hydroxy-3,3-dimethylbutanoate (CAS 1349685-12-6)
- 5-Iodo-N,N-dimethyl-4-(1-(methylsulfonyl)piperidin-4-yl)pyrimidin-2-amine (CAS 1361111-99-0)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com