1-[3-[4-[2-[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]-2-propen-1-one CAS 1629267-75-9
| CAS No. | 1629267-75-9 |
| Molecular Formula | C21H27ClN4O3 |
| Molecular Weight | 418.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-[3-[4-[2-[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]-2-propen-1-one (C21H27ClN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-[3-[4-[2-[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]-2-propen-1-one (CAS 1629267-75-9) is a high-purity analytical reference standard with the molecular formula C21H27ClN4O3 and a molecular weight of 418.92 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[3-[4-[2-[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]-2-propen-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27ClN4O3 |
| Molecular Weight | 418.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
- 4,6-Di([1,1'-biphenyl]-4-yl)-2-chloropyrimidine (CAS 1421599-29-2)
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- 4-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]phenyl 4-tert-butylbenzoate (CAS 331461-31-5)
- 4-([1,1':3',1''-Terphenyl]-5'-yl)-6-chloro-2-phenylpyrimidine (CAS 1852465-84-9)
- 3-Perylenecarboxaldehyde (CAS 35438-63-2)
- Novokinin (CAS 358738-77-9)
- 3-(Bis(2-hydroxyethyl)amino)propanenitrile (CAS 17209-72-2)
- Methyl 2-[(2Z)-azepan-2-ylidene]-2-cyanoacetate (CAS 1071933-02-2)
- Methyl 3-hydroxy-4-(hydroxymethyl)benzoate (CAS 71780-40-0)
- 1-(1,3-benzoxazol-2-yl)cyclopropan-1-amine (CAS 1159878-36-0)
- Desmethoxy-metobromuron (CAS 20680-07-3)
- Methyl 3-chloro-5-methylisonicotinate (CAS 1256791-82-8)
- 3,4-Dimethoxy-1,2,5-thiadiazole (CAS 55904-37-5)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
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