N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide CAS 573945-54-7
| CAS No. | 573945-54-7 |
| Molecular Formula | C18H19ClN6O2S |
| Molecular Weight | 418.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573945-54-7), a certified reference material (molecular formula C18H19ClN6O2S, MW 418.90 g/mol) for analytical method development and quality control.
The molecular framework of N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (C18H19ClN6O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H19ClN6O2S |
| Molecular Weight | 418.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(5-chloro-2-methoxyphenyl)-2-(3,5-diphenyl-1H-1,2,4-triazol-1-yl)acetamide (CAS 444152-89-0)
- 1-[3-[4-[2-[(4-Chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]-2-propen-1-one (CAS 1629267-75-9)
- 4-chloro-N'-(4,5-dihydronaphtho[1,2-b]thiophen-2-ylcarbonyl)benzenesulfonohydrazide 477888-02-1 KS-000034L1 (CAS 477888-02-1)
- 2-((4-Chloro-N-phenylphenyl)sulfonamido)-N-(4-fluorophenyl)acetamide (CAS 339102-60-2)
- 5-((2-Chloro-6-fluorobenzyl)thio)-8,9-dimethoxy-2-methyl-[1,2,4]triazolo[1,5-c]quinazoline (CAS 860611-08-1)
- N-(5-Chloro-2-methoxyphenyl)-2-(4-methoxyphenyl)quinoline-4-carboxamide (CAS 312920-43-7)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-2-methylpropyl)-4-methoxybenzamide (CAS 478246-01-4)
- N-(2-Chloro-4-nitrophenyl)-2-((3-((phenylamino)methyl)-1H-1,2,4-triazol-5-yl)thio)acetamide (CAS 332357-64-9)
Recommended Standards
- N-(4-(Benzo[d]thiazol-2-yl)phenyl)-7-chloro-6-methoxyquinazolin-4-amine (CAS 920520-21-4)
- 4-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]phenyl 4-tert-butylbenzoate (CAS 331461-31-5)
- 2-Bromo-5-iodo-1,3-bis(trifluoromethyl)benzene (CAS 2383655-21-6)
- 4,6-Di([1,1'-biphenyl]-4-yl)-2-chloropyrimidine (CAS 1421599-29-2)
- 5-(2-Chlorobenzyl)-2-mercapto-6-methylpyrimidin-4-ol (CAS 500156-98-9)
- Benzyl 2-(6-oxo-1,6-dihydropyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352482-00-8)
- 4-(5-(4-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)benzaldehyde (CAS 480391-18-2)
- 6'-Ethynyl-[2,2'-bipyridine]-6-carbaldehyde (CAS 327994-98-9)
- 2-(3-Chlorobenzyl)-1H-pyrrole (CAS 1706446-48-1)
- Methyl 3-cyano-2-methylbenzoate (CAS 93340-09-1)
- 3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)aniline (CAS 2803281-62-9)
- 3-Bromo-5-cyano-2-(difluoromethyl)benzoic acid (CAS 1805411-87-3)
- 1-{[1,1'-Biphenyl]-4-yl}-2-(4-nitro-1h-pyrazol-1-yl)ethan-1-one (CAS 1240568-22-2)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com