5-Amino-2-chloro-4-methylphenol CAS 16296-57-4
| CAS No. | 16296-57-4 |
| Molecular Formula | C7H8ClNO |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-2-chloro-4-methylphenol.
5-Amino-2-chloro-4-methylphenol (CAS 16296-57-4) is a high-purity analytical reference standard with the molecular formula C7H8ClNO and a molecular weight of 157.60 g/mol.
The molecular framework of 5-Amino-2-chloro-4-methylphenol (C7H8ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Amino-2-chloro-4-methylphenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- (3-Amino-4-chlorophenyl)methanol (CAS 104317-94-4)
- (4-Amino-3-chlorophenyl)methanol (CAS 113372-69-3)
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- 3-Amino-2-chlorobenzyl Alcohol (CAS 136774-74-8)
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- (2-Amino-5-chlorophenyl)methanol (CAS 37585-25-4)
Recommended Standards
- 2-Chloro-6-methylpyridine-3,4-diamine (CAS 1624261-30-8)
- (3-Chloro-6-methylpyrazin-2-yl)methanamine (CAS 1664384-90-0)
- 3-(Chloromethyl)-2-methylpyridine 1-oxide (CAS 162046-68-6)
- 5-Chloro-6-methylpyridine-2,3-diamine (CAS 168123-97-5)
- 4'-Ethyl-[1,1'-biphenyl]-4-ol (CAS 21345-28-8)
- Tert-butyl 3-(3-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate (CAS 1622834-55-2)
- Methyl 3-(bromomethyl)-1-benzofuran-2-carboxylate (CAS 58763-73-8)
- Ethyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)cyclohexane-1-carboxylate (CAS 2365173-46-0)
- 2-(3-(2-Chloroethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1256359-00-8)
- 2-(3,4-Difluorophenyl)-2,2-difluoroacetic Acid (CAS 915030-48-7)
- 3-(2-(Allylthio)ethyl)thietane 1,1-dioxide (CAS 1878955-64-6)
- 1-Amino-3-(dibenzylamino)propan-2-ol (CAS 50456-65-0)
- N-(2-Benzoylphenyl)-2-{[(1R)-1-phenylethyl]amino}acetamide (CAS 1219198-32-9)
- Peptide 436 (CAS CATO-CPTD788436)
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