(3-Chloro-6-methylpyrazin-2-yl)methanamine CAS 1664384-90-0
| CAS No. | 1664384-90-0 |
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(3-Chloro-6-methylpyrazin-2-yl)methanamine (CAS 1664384-90-0), molecular formula C6H8ClN3 and molecular weight 157.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3-Chloro-6-methylpyrazin-2-yl)methanamine (C6H8ClN3) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (3-Chloro-6-methylpyrazin-2-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-N2-methylpyridine-2,3-diamine (CAS 100114-37-2)
- 4-Chloro-3-ethoxypyridine (CAS 1003711-81-6)
- 5-Chloro-2,3-dimethylpyridine 1-oxide (CAS 1015057-46-1)
- 2-Chloro-5-(methoxymethyl)pyridine (CAS 1016534-59-0)
- 3-Chloro-5-methoxyaniline (CAS 10272-06-7)
- 3-Chloro-5-(methylamino)phenol (CAS 1082113-30-1)
- (6-Chloro-2-methylpyridin-3-yl)methanol (CAS 1093879-95-8)
- 2-Chloro-4-methoxy-5-methylpyridine (CAS 1122090-84-9)
Recommended Standards
- 5-Amino-2-chloro-4-methylphenol (CAS 16296-57-4)
- 5-Chloro-6-methylpyridine-2,3-diamine (CAS 168123-97-5)
- 2-Chloro-6-methylpyridine-3,4-diamine (CAS 1624261-30-8)
- 6-Chloro-5-methylpyridine-2,3-diamine (CAS 1691252-03-5)
- 1-(4-Hydroxybenzo[d]oxazol-2-yl)ethanone (CAS 1803858-21-0)
- 3-(5-Fluoro-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione (CAS 2696383-01-2)
- (S)-6,6'-diiodo-4,4'-dimethyl-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 2050190-03-7)
- ethyl {[4-(1-methyl-1H-pyrazol-3-yl)pyrimidin-2-yl]thio}acetate (CAS 1006323-19-8)
- 2-Phenyl-2-{[4-(propan-2-yl)phenyl]sulfanyl}acetic acid (CAS 938287-63-9)
- 4-((4-Amino-6-(5-chloro-1,3-dihydrobenzo[de]isochromen-6-yl)-1,3,5-triazin-2-yl)thio)butanoic acid (CAS 959763-05-4)
- 4-[(4-Chlorophenyl)methyl]-2H,3H,4H,5H-thieno[3,2-f][1,4]thiazepin-5-one (CAS 339105-75-8)
- (1R,2S)-2-phenylcyclohexan-1-amine (CAS 1011-11-6)
- Valdecoxib-13C2,15N (CAS 1189428-23-6)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
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