3,3-Difluoro-1-Methyl-2-Pyrrolidinone CAS 162970-50-5
| CAS No. | 162970-50-5 |
| Molecular Formula | C5H7F2NO |
| Molecular Weight | 135.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3,3-Difluoro-1-Methyl-2-Pyrrolidinone (CAS 162970-50-5), molecular formula C5H7F2NO and molecular weight 135.11 g/mol, is a CATO reference standard with documented purity and traceability.
3,3-Difluoro-1-Methyl-2-Pyrrolidinone (C5H7F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3,3-Difluoro-1-Methyl-2-Pyrrolidinone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7F2NO |
| Molecular Weight | 135.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- (S)-4,4-Difluoropyrrolidine-2-carbaldehyde (CAS 1357281-62-9)
- 4-(Difluoromethyl)pyrrolidin-2-one (CAS 1803589-29-8)
- N-(3,3-difluorocyclobutyl)formamide (CAS 1355328-30-1)
- (R)-4,4-Difluoropyrrolidine-2-carbaldehyde (CAS 2277300-69-1)
- Casanthranol (CAS 8024-48-4)
- 4-Phenyl-n-(2-phenylethyl)butanamide (CAS 83697-66-9)
- L-Phenylalanine benzyl ester (CAS 962-39-0)
- 722GHL96BJ 2211-64-5 N-Hydroxycyclohexylamine Cyclohexylhydroxylamine Hydroxylamine, N-cyclohexyl- 4-15-00-00003 (Beilstein Handbook Reference) BRN 0605426 N-Cyclohexylhydroxylamine EINECS 218-650-0 UNII-722GHL96BJ (CAS 2211-64-5)
- 5-Bromo-2-((tetrahydro-2H-pyran-4-yl)oxy)pyrimidine (CAS 1340125-32-7)
- (1,1-Difluorospiro[2.3]hexan-5-yl)methanamine hydrochloride (CAS 2098022-90-1)
- n-Ethyl-1h-imidazol-2-amine (CAS 126828-67-9)
- 6-Bromo-5,8-bis((2-methoxyethoxy)methoxy)-2,2-dimethyl-2H-chromene (CAS 557757-31-0)
- 4,5-Dimethoxy-2-(1h-pyrrol-1-yl)benzoic acid (CAS 55540-38-0)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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