(3,4-Difluorophenyl)methanesulfonyl chloride CAS 163295-73-6

Purity 97%+In StockPharmaceutical Standards
CAS No.163295-73-6
Molecular FormulaC7H5ClF2O2S
Molecular Weight226.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3,4-Difluorophenyl)methanesulfonyl chloride CAS 163295-73-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3,4-Difluorophenyl)methanesulfonyl chloride.

(3,4-Difluorophenyl)methanesulfonyl chloride (CAS 163295-73-6), molecular formula C7H5ClF2O2S and molecular weight 226.63 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C7H5ClF2O2S, (3,4-Difluorophenyl)methanesulfonyl chloride contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (3,4-Difluorophenyl)methanesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H5ClF2O2S
Molecular Weight226.63 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF/Cl-containing
Sulfur Atoms1

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Why CATO?