(2,3-Difluorophenyl)methanesulfonyl chloride CAS 886498-49-3
| CAS No. | 886498-49-3 |
| Molecular Formula | C7H5ClF2O2S |
| Molecular Weight | 226.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2,3-Difluorophenyl)methanesulfonyl chloride (CAS 886498-49-3), molecular formula C7H5ClF2O2S and molecular weight 226.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2,3-Difluorophenyl)methanesulfonyl chloride (C7H5ClF2O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures (2,3-Difluorophenyl)methanesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2O2S |
| Molecular Weight | 226.63 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluorophenyl Standards
- (3,4-Difluorophenyl)methanesulfonyl chloride (CAS 163295-73-6)
- (3,5-Difluorophenyl)methanesulfonyl chloride (CAS 163295-74-7)
- (2,6-Difluorophenyl)methanesulfonyl chloride (CAS 179524-60-8)
- (2,5-Difluorophenyl)methanesulfonyl chloride (CAS 179524-62-0)
- (2,4-Difluorophenyl)methanesulfonyl chloride (CAS 179524-68-6)
- 2-(2,5-Difluorophenyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 1096880-44-2)
- 1-[(2,3-Difluorophenyl)methyl]-1,4-diazepane (CAS 1153434-52-6)
- 1-[(3,4-Difluorophenyl)methyl]-1,4-diazepane (CAS 1178292-54-0)
Recommended Standards
- (1-(4-Chloro-2-fluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 2379321-78-3)
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- 2,3-Difluoro-5-methylbenzenesulfonyl chloride (CAS 1807099-50-8)
- 2-(1-Chloroethyl)-5-(4-fluorophenyl)-1,3,4-oxadiazole (CAS 854137-54-5)
- 4-(4-Ethynylphenyl)butanoic acid (CAS 2131053-53-5)
- 5-Methyl-6-(propylamino)nicotinaldehyde (CAS 1355232-54-0)
- N-(2,3-dichlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide (CAS 477857-85-5)
- (4-Methyl-pyridin-2-yl)-piperidin-4-yl-amine hydrochloride (CAS 1185310-83-1)
- 1-(3-Chloropropyl)-3,5,7,9,11,13,15-heptakis(2-methylpropyl)pentacyclo[9.5.1.13,9.15,15.17,13]octasiloxane (CAS 480438-84-4)
- 5-Methyl-1-(4-nitrophenyl)-N-propyl-1H-1,2,4-triazole-3-carboxamide (CAS 321431-10-1)
- H-Glu(Tyr-OH)-OH（TFA Salt） (CAS 7432-23-7（free base）)
- (4aR,5aS)-Ethyl 5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazole-3-carboxylate (CAS 2655557-59-6)
- 3-(propan-2-yloxy)pyridine-2-carboximidamide (CAS 1515456-27-5)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
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