2-(Chloromethyl)-6-fluoroquinazolin-4(3H)-one CAS 163311-08-8
| CAS No. | 163311-08-8 |
| Molecular Formula | C9H6ClFN2O |
| Molecular Weight | 212.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Chloromethyl)-6-fluoroquinazolin-4(3H)-one (CAS 163311-08-8) is a high-purity analytical reference standard with the molecular formula C9H6ClFN2O and a molecular weight of 212.61 g/mol.
2-(Chloromethyl)-6-fluoroquinazolin-4(3H)-one (C9H6ClFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-(Chloromethyl)-6-fluoroquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClFN2O |
| Molecular Weight | 212.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 5-(Chloromethyl)-1-(3-fluorophenyl)-1h-1,2,3,4-tetrazole (CAS 1105194-91-9)
- 5-(Chloromethyl)-3-(2-fluorophenyl)-1,2,4-oxadiazole (CAS 110704-45-5)
- 2-(Chloromethyl)-5-fluoroquinazolin-4(3H)-one (CAS 1263413-73-5)
- 3-(chloromethyl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (CAS 166179-37-9)
- 2-(Chloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole (CAS 350672-17-2)
- 2-(Chloromethyl)-5-(3-fluorophenyl)-1,3,4-oxadiazole (CAS 350672-16-1)
- 2-(Chloromethyl)-5-(4-fluorophenyl)-1,3,4-oxadiazole (CAS 350672-14-9)
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Recommended Standards
- 8-Chloro-5-fluoro-3-methoxy-1,7-naphthyridine (CAS 1600511-84-9)
- 4-Chloro-7-fluoro-6-methoxyquinazoline (CAS 159768-48-6)
- 8-Chloro-6-fluoro-2-methylquinazolin-4(3H)-one (CAS 1696832-46-8)
- 4-Chloro-6-fluoro-8-methoxyquinazoline (CAS 1565090-05-2)
- 6-Bromo-4-fluoroisoindoline (CAS 689214-92-4)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((3-(4-methoxyphenyl)-2-methylisoxazolidin-5-yl)methyl)-N'-methylmethanesulfonohydrazide (CAS 339276-44-7)
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- TC-G 1000 (CAS 245744-18-7)
- 3-Methyl-1-oxo-N-(quinoxalin-6-yl)isochromane-3-carboxamide (CAS 921118-69-6)
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- 2,3-Difluoro-4'-methylsulfanylbiphenyl (CAS 157248-20-9)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
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