N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((3-(4-methoxyphenyl)-2-methylisoxazolidin-5-yl)methyl)-N'-methylmethanesulfonohydrazide CAS 339276-44-7
| CAS No. | 339276-44-7 |
| Molecular Formula | C20H24ClF3N4O4S |
| Molecular Weight | 508.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((3-(4-methoxyphenyl)-2-methylisoxazolidin-5-yl)methyl)-N'-methylmethanesulfonohydrazide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((3-(4-methoxyphenyl)-2-methylisoxazolidin-5-yl)methyl)-N'-methylmethanesulfonohydrazide (CAS 339276-44-7), a certified reference material (molecular formula C20H24ClF3N4O4S, MW 508.94 g/mol) for analytical method development and quality control.
The molecular framework of N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((3-(4-methoxyphenyl)-2-methylisoxazolidin-5-yl)methyl)-N'-methylmethanesulfonohydrazide (C20H24ClF3N4O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24ClF3N4O4S |
| Molecular Weight | 508.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
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Recommended Standards
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- Doxycycline Impurity 23 (CAS CATO-C4X-193123)
- CMC2026 Impurity 4 (CAS CATO-C4X-22664)
- Clomocycline (CAS 1181-54-0)
- 5-(3-Methoxyphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 667921-14-4)
- 2-[(4-Chlorophenyl)sulfanyl]-N-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]acetamide (CAS 478260-44-5)
- Methyl 4-bromo-1-oxo-1,2-dihydroisoquinoline-7-carboxylate (CAS 1264209-67-7)
- 3-Ethylpyrrolidine-1-sulfonyl chloride (CAS 1564741-01-0)
- N,2-Dimethyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-5-amine (CAS 1707568-82-8)
- 23273-82-7 Phosphoric acid--N~1~-(3-aminopropyl)butane-1,4-diamine--water (1/1/6) DTXSID50725094 (CAS 23273-82-7)
- 3-isopropoxy-4-tributylstannyl-cyclobut-3-ene-1,2-dione (CAS 129034-70-4)
- tert-Butyl 2-(6-(cyclobutylamino)pyridin-3-yl)piperidine-1-carboxylate (CAS 1352492-72-8)
- Isopropyl 5-oxopyrrolidine-2-carboxylate (CAS 85136-11-4)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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