N-(4-Oxoquinazolin-3(4H)-yl)acetamide CAS 16347-87-8

Purity 97%+In StockPharmaceutical Standards
CAS No.16347-87-8
Molecular FormulaC10H9N3O2
Molecular Weight203.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Oxoquinazolin-3(4H)-yl)acetamide CAS 16347-87-8 chemical structure

Description

The occurrence of N-(4-Oxoquinazolin-3(4H)-yl)acetamide is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(4-Oxoquinazolin-3(4H)-yl)acetamide (CAS 16347-87-8) is a high-purity analytical reference standard with the molecular formula C10H9N3O2 and a molecular weight of 203.20 g/mol.

The molecular framework of N-(4-Oxoquinazolin-3(4H)-yl)acetamide (C10H9N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H9N3O2
Molecular Weight203.20 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms3

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