5-[3-(trifluoromethyl)phenyl]pyridin-2-amine CAS 163563-17-5

Purity 97%+In StockPharmaceutical Standards
CAS No.163563-17-5
Molecular FormulaC12H9F3N2
Molecular Weight238.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-[3-(trifluoromethyl)phenyl]pyridin-2-amine CAS 163563-17-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 238.21 g/mol gives 5-[3-(trifluoromethyl)phenyl]pyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-[3-(trifluoromethyl)phenyl]pyridin-2-amine (CAS 163563-17-5) is a high-purity analytical reference standard with the molecular formula C12H9F3N2 and a molecular weight of 238.21 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 5-[3-(trifluoromethyl)phenyl]pyridin-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 238.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-[3-(trifluoromethyl)phenyl]pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9F3N2
Molecular Weight238.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF-containing
Nitrogen Atoms2

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