2-Chloro-4-phenylnicotinonitrile CAS 163563-64-2
| CAS No. | 163563-64-2 |
| Molecular Formula | C12H7ClN2 |
| Molecular Weight | 214.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-4-phenylnicotinonitrile (C12H7ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Chloro-4-phenylnicotinonitrile (CAS 163563-64-2) is a high-purity analytical reference standard with the molecular formula C12H7ClN2 and a molecular weight of 214.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-4-phenylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7ClN2 |
| Molecular Weight | 214.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- 4-Chloro-1-cyclopentyl-1h-pyrazole-5-carboxylic acid (CAS 1006493-95-3)
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Recommended Standards
- Methyl 5-chloro-2-methoxy-3-methylbenzoate (CAS 16220-96-5)
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- tert-Butyl 5-chloropyrazine-2-carboxylate (CAS 169335-50-6)
- 3-Bromo-7-(methylsulfonyl)quinoline (CAS 1956331-49-9)
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- 4-(1h-Pyrazol-1-yl)butan-1-ol (CAS 1156067-60-5)
- 2-Methyl-4-(pyrazol-1-yl)phenylboronic acid (CAS 858523-47-4)
- 1,4,6-Androstatriene-17β-ol-3-one (CAS 4075-12-1)
- 1,1,1-Trifluoro-3-(1H-pyrazol-1-yl)propan-2-ol (CAS 1342051-08-4)
- 3-Bromo-5,6-dihydropyridin-2(1H)-one (CAS 1258849-38-5)
- Niraparib Impurity 6 (CAS 1369926-38-4)
- (R)-N-(2-((1-(3-(Trifluoromethyl)phenyl)ethyl)amino)-1H-benzo[d]imidazol-4-yl)acetamide (CAS 1446770-54-2)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
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