Acetylcysteine Impurity 18 CAS 1637-71-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1637-71-4
Molecular FormulaC3H7NO5S2
Molecular Weight201.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Acetylcysteine Impurity 18 CAS 1637-71-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 201.22 g/mol gives Acetylcysteine Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Acetylcysteine Impurity 18 (CAS 1637-71-4, C3H7NO5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Acetylcysteine Impurity 18 (C3H7NO5S2) contains an amide group, a sulfone group, a carboxylic acid group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Acetylcysteine Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC3H7NO5S2
Molecular Weight201.22 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1957
Nitrogen Atoms1
Sulfur Atoms2

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