Dolutegravir Impurity 14 CAS 127958-23-0
| CAS No. | 127958-23-0 |
| Molecular Formula | C9H15NO4 |
| Molecular Weight | 201.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Dolutegravir Impurity 14 (CAS 127958-23-0), a pharmacopoeial impurity reference standard (molecular formula C9H15NO4, MW 201.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H15NO4, Dolutegravir Impurity 14 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 201.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Dolutegravir Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H15NO4 |
| Molecular Weight | 201.22 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
Related Dolutegravir Standards
- Dolutegravir Impurity 20 (CAS 1341434-11-4)
- Dolutegravir Impurity 19 (CAS 1916490-96-4)
- Dolutegravir Impurity 27 (CAS 1335210-31-5)
- Dolutegravir Amide (CAS 1485081-26-2)
- Dolutegravir Impurity 67 (CAS CATO-C4X-162067)
- Dolutegravir Impurity N13 (CAS 1246616-73-8)
- Dolutegravir Impurity 51 (CAS CATO-C4X-162051)
- Dolutegravir Impurity 43 (CAS 2651309-06-5)
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- Ketorolac Impurity 25 (CAS CATO-C4X-166925)
- Roxadustat impurity 110 (CAS CATO-C4X-2213110)
- Etrasimod impurity 15 (CAS CATO-C4X-321415)
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- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
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