2-(1H-benzo[d]imidazol-1-yl)-1-(4-methoxyphenyl)ethan-1-ol CAS 163729-46-2

Purity 97%+In StockPharmaceutical Standards
CAS No.163729-46-2
Molecular FormulaC16H16N2O2
Molecular Weight268.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1H-benzo[d]imidazol-1-yl)-1-(4-methoxyphenyl)ethan-1-ol CAS 163729-46-2 chemical structure

Description

The occurrence of 2-(1H-benzo[d]imidazol-1-yl)-1-(4-methoxyphenyl)ethan-1-ol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(1H-benzo[d]imidazol-1-yl)-1-(4-methoxyphenyl)ethan-1-ol (CAS 163729-46-2), molecular formula C16H16N2O2 and molecular weight 268.31 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(1H-benzo[d]imidazol-1-yl)-1-(4-methoxyphenyl)ethan-1-ol (C16H16N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H16N2O2
Molecular Weight268.31 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Nitrogen Atoms2

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