2-Ethoxy-4-nitroaniline CAS 16383-89-4
| CAS No. | 16383-89-4 |
| Molecular Formula | C8H10N2O3 |
| Molecular Weight | 182.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Ethoxy-4-nitroaniline.
2-Ethoxy-4-nitroaniline (CAS 16383-89-4), molecular formula C8H10N2O3 and molecular weight 182.18 g/mol, is a CATO reference standard with documented purity and traceability.
2-Ethoxy-4-nitroaniline (C8H10N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O3 |
| Molecular Weight | 182.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Ethoxy Standards
- 3-Ethoxy-4-nitroaniline (CAS 116435-75-7)
- 2-Ethoxy-3-methyl-5-nitropyridine (CAS 1354224-95-5)
- 2-Ethoxy-5-nitroaniline (CAS 136-79-8)
- 6-Ethoxy-2-methylpyrimidine-4-carboxylic acid (CAS 1707374-04-6)
- 4-Ethoxy-3-nitroaniline (CAS 1777-87-3)
- 2-Ethoxy-4-methyl-5-nitropyridine (CAS 1881331-60-7)
- 2-Ethoxy-6-nitroaniline (CAS 6036-46-0)
- 3-Ethoxy-2-methyl-6-nitropyridine (CAS 73101-78-7)
Recommended Standards
- Pyrrolo[1,2-a]pyrazine-1,4,6(7H)-trione,tetrahydro-3-methyl-,(3S,8aS)-(8CI) (CAS 16364-61-7)
- 2-Hydroxy-2-(4-nitrophenyl)ethylamine (CAS 16428-47-0)
- 6-Ethyl-1-methyl-5-nitropyridin-2(1H)-one (CAS 1624262-15-2)
- 2,6-Bis(methylamino)pyrimidine-4-carboxylic acid (CAS 16490-29-2)
- n,n-Dimethyl-2-((4-methylbenzyl)amino)acetamide (CAS 1020937-66-9)
- 4-Methyl-2-(thiophen-2-yl)aniline (CAS 926237-35-6)
- 1H-Cyclopropa[d]pyrrolo[1,2-b]pyridazine (CAS 175894-07-2)
- 2-(5-Bromo-2-hydroxyphenyl)benzimidazole (CAS 62871-28-7)
- 1-IOdo-1h,1h,2h,2h-perfluoro(4,7,10,13,16-pentamethyl-5,8,11,14,17-pentaoxaeicosane) (CAS 1212369-20-4)
- 4-Cyclopropyl-6-methoxypyrimidin-2-amine (CAS 21666-65-9)
- 3-Cyclopropoxy-6-(methylsulfonamido)picolinic acid (CAS 1243346-33-9)
- {[4-(Benzyloxy)phenyl]methyl}({[4-(trifluoromethyl)phenyl]methyl})amine (CAS 1186195-40-3)
- 3-(2-Methylpropoxy)propanenitrile (CAS 58936-28-0)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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