2-Hydroxy-2-(4-nitrophenyl)ethylamine CAS 16428-47-0
| CAS No. | 16428-47-0 |
| Molecular Formula | C8H10N2O3 |
| Molecular Weight | 182.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 182.18 g/mol gives 2-Hydroxy-2-(4-nitrophenyl)ethylamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Hydroxy-2-(4-nitrophenyl)ethylamine (CAS 16428-47-0) is a high-purity analytical reference standard with the molecular formula C8H10N2O3 and a molecular weight of 182.18 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 2-Hydroxy-2-(4-nitrophenyl)ethylamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Hydroxy-2-(4-nitrophenyl)ethylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O3 |
| Molecular Weight | 182.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- cis-3-(benzyloxy)cyclobutanamine (CAS 206660-72-2)
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- Enarodustat Impurity 22 (CAS CATO-C4X-322822)
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