Benzyl 3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate CAS 1638761-26-8
| CAS No. | 1638761-26-8 |
| Molecular Formula | C12H13F2NO3 |
| Molecular Weight | 257.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Benzyl 3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Benzyl 3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate (CAS 1638761-26-8) is a high-purity analytical reference standard with the molecular formula C12H13F2NO3 and a molecular weight of 257.23 g/mol.
Structurally, Benzyl 3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate (C12H13F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 257.23 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Benzyl 3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F2NO3 |
| Molecular Weight | 257.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
- 2-(2,6-Difluoro-benzoylamino)-3-methyl-butyric acid (CAS 1396972-19-2)
- Methyl 2,5-difluoro-4-morpholinobenzoate (CAS 1858251-27-0)
- 2,3-Difluoro-6-pivalamidobenzoic acid (CAS 874784-13-1)
- 4,4-Difluoro-3-[(phenylmethyl)amino]butanoic acid ethyl ester (CAS 81982-49-2)
- N'-(4,6-Difluoro-1,3-benzothiazol-2-yl)-N,N-dimethylethane-1,2-diamine (CAS 1105188-23-5)
- 6-(2,2-Difluoro-2-phenylethoxy)hexan-1-amine (CAS 915132-93-3)
- (3,4-Difluoro-5-(4-hydroxypiperidin-1-yl)phenyl)boronic acid (CAS 1704068-71-2)
- (3,4-Difluoro-2-pivalamidophenyl)boronic acid (CAS 676540-81-1)
Recommended Standards
- 3-[(3,5-difluorophenyl)carbamoyl]-2,2-dimethylpropanoic acid (CAS 1485705-79-0)
- 2-[4-(Trifluoromethyl)phenyl]thiazole-4-carbaldehyde (CAS 174006-70-3)
- Thiazol-2-yl(4-(trifluoromethyl)phenyl)methanone (CAS 147878-71-5)
- tert-Butyl (2,6-difluoro-4-formylphenyl)carbamate (CAS 1782542-58-8)
- (4-Bromo-1h-pyrrol-2-yl)(morpholino)methanone (CAS 900019-58-1)
- D-myo-Inositol, 1,2,6-tris(dihydrogen phosphate), xsodium salt (CAS 120965-76-6)
- 2-(2,4-Dichlorophenoxy)-6-phenyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338749-46-5)
- Isoquinolin-1-yl(p-tolyl)methanol (CAS 5467-96-9)
- 1-[(difluoromethyl)sulfanyl]-3-nitrobenzene (CAS 24933-39-9)
- N,s-diacetylcysteamine (CAS 1420-88-8)
- PUMECITINIB Impurity 4 (CAS CATO-C4X-35664)
- Pyridine-2-aldoxime (CAS 873-69-8)
- 2-((3,4-Dimethylphenyl)thio)ethanol (CAS 13290-28-3)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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