6-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine CAS 1638763-80-0
| CAS No. | 1638763-80-0 |
| Molecular Formula | C6H5IN4 |
| Molecular Weight | 260.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 1638763-80-0), molecular formula C6H5IN4 and molecular weight 260.04 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, iodine substitution, an aromatic ring system, 6-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 260.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5IN4 |
| Molecular Weight | 260.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 4 |
Related Iodo Standards
- 3-Iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1219636-66-4)
- 5-Iodo-[1,2,4]triazolo[1,5-a]pyridin-2-amine (CAS 1245645-07-1)
- 3-Iodo-1H-pyrazolo[3,4-b]pyridin-5-amine (CAS 1260681-83-1)
- 7-Iodo-1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 1350648-21-3)
- 3-Iodo-2H-pyrazolo[4,3-b]pyridin-6-amine (CAS 1352393-59-9)
- 5-Iodo-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1392152-87-2)
- 3-Iodo-6-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1415559-47-5)
- 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 1416354-36-3)
Recommended Standards
- 7-Iodo-5H-pyrrolo[3,2-d]pyrimidin-2-amine (CAS 1638761-03-1)
- 2-Bromo-4-methyl-5-nitrobenzoic acid (CAS 1698117-49-5)
- Methyl 4-Bromo-2-nitrobenzoate (CAS 158580-57-5)
- 4-Bromo-5-Methyl-2-nitrobenzoic acid (CAS 1708958-91-1)
- 5-Bromo-2-fluoro-4-methylbenzaldehyde (CAS 497224-12-1)
- 2-[(4-tert-butylphenyl)formamido]-3-methylbutanoic acid (CAS 1396965-62-0)
- (3-(Azocan-1-ylmethyl)phenyl)methanamine (CAS 115174-13-5)
- 2-(Tert-butyl)-4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 2306269-50-9)
- 2-(5-Ethoxy-1-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1365941-91-8)
- (2-Bromo-6-fluoro-3-methoxyphenyl)methanol (CAS 1500279-77-5)
- 1,3,5-Tribromo-2-nitrobenzene (CAS 3463-40-9)
- N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide (CAS 284664-78-4)
- 2-(4-Bromophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (CAS 1285382-33-3)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
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