tert-Butyl ((4-aminobicyclo[2.1.1]hexan-1-yl)methyl)carbamate CAS 1638765-45-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1638765-45-3
Molecular FormulaC12H22N2O2
Molecular Weight226.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl ((4-aminobicyclo[2.1.1]hexan-1-yl)methyl)carbamate CAS 1638765-45-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 226.32 g/mol gives tert-Butyl ((4-aminobicyclo[2.1.1]hexan-1-yl)methyl)carbamate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

tert-Butyl ((4-aminobicyclo[2.1.1]hexan-1-yl)methyl)carbamate (CAS 1638765-45-3), molecular formula C12H22N2O2 and molecular weight 226.32 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of tert-Butyl ((4-aminobicyclo[2.1.1]hexan-1-yl)methyl)carbamate (C12H22N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl ((4-aminobicyclo[2.1.1]hexan-1-yl)methyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H22N2O2
Molecular Weight226.32 g/mol
AppearanceWhite to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1993
Nitrogen Atoms2

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