2-Cyano Loratadine CAS 860010-31-7
| CAS No. | 860010-31-7 |
| Molecular Formula | C23H22ClN3O2 |
| Molecular Weight | 407.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Cyano Loratadine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Cyano Loratadine (CAS 860010-31-7), a certified reference material (molecular formula C23H22ClN3O2, MW 407.89 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Cyano Loratadine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 407.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Cyano Loratadine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H22ClN3O2 |
| Molecular Weight | 407.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Cyano Standards
- 4-Cyano Loratadine (CAS 860010-33-9)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 924236-36-2)
- 2-Cyano-N-cyclohexyl-3-(2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide (CAS 477734-60-4)
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- Ethyl 2-cyano-3-(4-(2-((2,4-dimethylphenyl)amino)-2-oxoethoxy)-3-methoxyphenyl)acrylate (CAS 1164462-24-1)
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Recommended Standards
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