3-(Trifluoromethoxy)azetidine-3-carboxylic acid hydrochloride CAS 1638767-91-5
| CAS No. | 1638767-91-5 |
| Molecular Formula | C5H6F3NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(Trifluoromethoxy)azetidine-3-carboxylic acid hydrochloride (CAS 1638767-91-5) is a high-purity analytical reference standard with the molecular formula C5H6F3NO3HCl and a molecular weight of 221.56 g/mol.
Structurally, 3-(Trifluoromethoxy)azetidine-3-carboxylic acid hydrochloride (C5H6F3NO3HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 221.56 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(Trifluoromethoxy)azetidine-3-carboxylic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6F3NO3 HCl |
| Molecular Weight | 221.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
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Recommended Standards
- 2-(Bromomethyl)-1-chloro-3-methoxybenzene (CAS 83781-95-7)
- Antide (CAS 112568-12-4)
- 3-(3-(Methylthio)phenyl)-1H-pyrazol-5-amine (CAS 2169350-90-5)
- 6-(Methylthio)pyrimidine-2,4-diamine (CAS 4765-71-3)
- 3-Bromo-2-methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 934063-79-3)
- Modafinil USP Related Compound C (CAS 68524-30-1)
- 2-Bromo-4-chlorobenzoyl chloride (CAS 116779-74-9)
- 3-(Aminomethyl)-2-fluorobenzoic acid (CAS 1534353-00-8)
- Upadacitinib Impurity 51 (CAS 2270173-65-2)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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