(2R)-4,4-Difluoro-2-methylpyrrolidine CAS 1670259-97-8
| CAS No. | 1670259-97-8 |
| Molecular Formula | C5H9F2N |
| Molecular Weight | 121.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2R)-4,4-Difluoro-2-methylpyrrolidine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2R)-4,4-Difluoro-2-methylpyrrolidine (CAS 1670259-97-8) is a high-purity analytical reference standard with the molecular formula C5H9F2N and a molecular weight of 121.13 g/mol.
(2R)-4,4-Difluoro-2-methylpyrrolidine (C5H9F2N) contains fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2R)-4,4-Difluoro-2-methylpyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H9F2N |
| Molecular Weight | 121.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 3,3-Difluoro-1-methylcyclobutan-1-amine (CAS 1408076-03-8)
- 3,3-Difluoro-4-methylpyrrolidine (CAS 1554367-59-7)
- (2S)-4,4-Difluoro-2-methylpyrrolidine (CAS 1670259-98-9)
- 3,3-Difluoro-2-pyrrolidinone (CAS 162970-49-2)
- 2,2-Difluoro-cyclopropaneboronic acid (CAS 2408428-30-6)
- (+/-)-2,2-Difluoro-1-methylcyclopropan1-yl-methanol (CAS 1241675-78-4)
- (2,2-difluoro-1-methyl-cyclopropyl)methanol (CAS 128230-72-8)
- (2,2-Difluoro-3-methylcyclopropyl)methanol (CAS 509072-72-4)
Recommended Standards
- (3S)-3-(Difluoromethyl)pyrrolidine (CAS 1638784-47-0)
- (2,2-Difluorocyclobutyl)methanamine (CAS 1582718-52-2)
- 1-(1,1-Difluoroethyl)cyclopropan-1-amine (CAS 1780438-66-5)
- [1-(difluoromethyl)cyclopropyl]methanamine hydrochloride (CAS 1785097-21-3)
- 4-(Hydroxymethyl)-n,n-dimethylbenzenesulfonamide (CAS 58804-18-5)
- 2-Chloro-1-[3-(4-chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1h-pyrazol-1-yl]ethan-1-one (CAS 380196-88-3)
- (2E)-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-2-[(dimethylamino)methylidene]-3-oxobutanenitrile (CAS 339106-44-4)
- 1-(4-Chlorophenyl)-2-((5-(4-pentylcyclohexyl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 860610-97-5)
- Methyl 3-(benzyloxy)benzo[b]thiophene-2-carboxylate (CAS 722517-50-2)
- 1,3-Dibromo-2,4-difluorobenzene (CAS 219926-41-7)
- 2-Chloro-4-methyl-6-phenylimidazo[1,5-a]pyrimidine (CAS 79899-10-8)
- {2-[(9H-Xanthen-9-ylcarbonyl)amino]-1,3-thiazol-4-yl}acetic acid (CAS 931374-33-3)
- 2-((1-(3-Nitrophenyl)ethyl)amino)ethan-1-ol (CAS 1039973-04-0)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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