1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine hydrochloride CAS 1639350-46-1
| CAS No. | 1639350-46-1 |
| Molecular Formula | C8H13N3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine hydrochloride (CAS 1639350-46-1), a certified reference material (molecular formula C8H13N3OHCl, MW 203.67 g/mol) for analytical method development and quality control.
The molecular framework of 1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine hydrochloride (C8H13N3OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H13N3O HCl |
| Molecular Weight | 203.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Tetrahydro Standards
- 3-(Tetrahydro-2H-pyran-4-yl)benzoic acid (CAS 1000016-93-2)
- 10004-03-2 2-Phenyl-2,3,4,5-tetrahydro-1,4-benzoxazepine 7068AC C15H15NO (CAS 10004-03-2)
- 1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-4-carboxylic acid (CAS 1000576-23-7)
- 1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-5-carboxylic acid (CAS 1000576-28-2)
- 5-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline (CAS 100077-51-8)
- 1-((Tetrahydro-2H-pyran-2-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1000802-49-2)
- 4,5,6,7-Tetrahydro-1-phenyl-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 1000933-91-4)
- 7-Methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine (CAS 1001003-42-4)
Recommended Standards
- 6-Methoxy-2-(4-styrylphenyl)benzofuran (CAS 51358-02-2)
- 1-Bromo-4-difluoromethoxy-2-(trifluoromethoxy)benzene (CAS 1805024-71-8)
- 1-(1-Methyl-1H-pyrazol-3-yl)-N-((1-propyl-1H-pyrazol-3-yl)methyl)methanamine hydrochloride (CAS 1856076-20-4)
- Naproxen Impurity 7 (CAS CATO-C4X-17087)
- 2-(3-Methoxyphenyl)pyridine (CAS 4373-58-4)
- 2-(4-((1-(3-Hydroxy-1-oxo-1H-inden-2-yl)ethylidene)amino)phenyl)acetonitrile (CAS 1022589-85-0)
- Isavuconazole Impurity 124 (CAS CATO-C4X-1236124)
- 2-Butenedioic acid (2Z)-, homopolymer, butyl ester (CAS 68130-17-6)
- 2-Chloro-2-Fluoro-1-(2-Thienyl)Ethanone (CAS 58750-67-7)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
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