Edaravone Impurity N5 CAS 16394-90-4
| CAS No. | 16394-90-4 |
| Molecular Formula | C20H17N5O2 |
| Molecular Weight | 359.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Edaravone Impurity N5 (CAS 16394-90-4, C20H17N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H17N5O2, Edaravone Impurity N5 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 359.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17N5O2 |
| Molecular Weight | 359.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 5 |
Related Edaravone Standards
- Edaravone Impurity 14 (CAS CATO-C4X-106214)
- Edaravone impurity 54 (CAS CATO-C4X-106254)
- Edaravone Impurity 59 (CAS CATO-C4X-106259)
- Edaravone impurity 55 (CAS CATO-C4X-106255)
- Edaravone impurity 37 (CAS CATO-C4X-106237)
- Edaravone impurity 42 (CAS 153952-07-9)
- Edaravone impurity 53 (CAS 92558-29-7)
- Edaravone Impurity 58 (CAS CATO-C4X-106258)
Recommended Standards
- N-[2-(1-Pyrazolyl)benzyl]-5-(2-hydroxyphenyl)-1H-pyrazole-3-carboxamide (CAS 1470368-88-7)
- tert-Butyl N-({[4-(furan-2-amido)phenyl]carbamoyl}methyl)carbamate (CAS 1905922-36-2)
- tert-Butyl 4-(6-nitroquinoxalin-2-yl)piperazine-1-carboxylate (CAS 1417794-18-3)
- (1-(2-Hydroxyethyl)-3-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl)(2-hydroxyphenyl)methanone (CAS 796053-09-3)
- Ornidazole Impurity 109 (CAS CATO-C4X-1331109)
- Roxadustat Impurity 47 (CAS CATO-C4X-221347)
- Entacapone Impurity 6 (CAS 158693-01-7)
- 6-Hydroxybenzo[b]thiophene-2-sulfonamide (CAS 96803-89-3)
- 1-Methanesulfonyl-2-morpholino-4-nitrobenzene (CAS 1194974-72-5)
- N-Methyl-5-phenyl-4H-1,2,4-triazol-3-amine (CAS 54463-81-9)
- 4-Hydroxy-N-(4-methoxyphenyl)-2-oxo-1-phenyl-2,5-dihydro-1H-pyrrole-3-carboxamide (CAS 1221504-66-0)
- 8-bromo-2-ethylsulfanyl-6-methyl-chromen-4-one (CAS 2715284-54-9)
- 10,20-Dimethoxyhexacyclo[17.8.0.0^{2,11}.0^{3,8}.0^{13,17}.0^{22,27}]heptacosa-1(19),2,4,6,8,10,13(17),15,20,22,24,26-dodecaene (CAS 1417714-08-9)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com