Edaravone Impurity 59 CAS CATO-C4X-106259
| CAS No. | CATO-C4X-106259 |
| Molecular Formula | C20H16N4O3 |
| Molecular Weight | 360.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Edaravone Impurity 59 (CAS CATO-C4X-106259) is a certified pharmaceutical impurity reference standard with the molecular formula C20H16N4O3 and a molecular weight of 360.37 g/mol.
Based on its molecular formula C20H16N4O3, Edaravone Impurity 59 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 360.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16N4O3 |
| Molecular Weight | 360.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Edaravone Standards
- Edaravone impurity 55 (CAS CATO-C4X-106255)
- Edaravone Impurity N5 (CAS 16394-90-4)
- Edaravone Impurity 14 (CAS CATO-C4X-106214)
- Edaravone impurity 54 (CAS CATO-C4X-106254)
- Edaravone impurity 37 (CAS CATO-C4X-106237)
- Edaravone impurity 42 (CAS 153952-07-9)
- Edaravone impurity 53 (CAS 92558-29-7)
- Edaravone Impurity 58 (CAS CATO-C4X-106258)
Recommended Standards
- tert-Butyl 3-(2-(trifluoromethoxy)benzyl)piperazine-1-carboxylate (CAS 886773-81-5)
- Atogepant Impurity 14 (CAS CATO-C4X-328514)
- tert-Butyl 2-(3-(trifluoromethoxy)benzyl)piperazine-1-carboxylate (CAS 886774-02-3)
- H-Arg-Gly-Glu-OH (CAS 20274-91-3)
- Flurbiprofen Impurity 138 (CAS 88975-22-8)
- Lefamulinum Impurity 20 (CAS CATO-C4X-304720)
- Daprodustat Impurity 24 (CAS CATO-C4X-240724)
- Benzyl (2-azaspiro[3.3]heptan-6-yl)carbamate (CAS 1440962-13-9)
- 4-chloro-3H-pyrrolo[2,3-c]quinoline (CAS 1467089-08-2)
- 4-((9H-fluoren-9-ylidene)methyl)-N,N-dimethylaniline (CAS 2871-86-5)
- 5-Chloropentan-1-amine hydrochloride (CAS 1745-60-4)
- n-{2-[(4-fluorophenyl)sulfanyl]ethyl}aniline (CAS 1275711-70-0)
- 5,7-Dichloroquinolin-2(1H)-one (CAS 835903-13-4)
- Exenatide Acetate (CAS 141732-76-5)
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