N-(1,4-dioxo-3-(4-phenylpiperazin-1-yl)-1,4-dihydronaphthalen-2-yl)benzamide CAS 1640259-27-3
| CAS No. | 1640259-27-3 |
| Molecular Formula | C27H23N3O3 |
| Molecular Weight | 437.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(1,4-dioxo-3-(4-phenylpiperazin-1-yl)-1,4-dihydronaphthalen-2-yl)benzamide.
N-(1,4-dioxo-3-(4-phenylpiperazin-1-yl)-1,4-dihydronaphthalen-2-yl)benzamide (CAS 1640259-27-3), molecular formula C27H23N3O3 and molecular weight 437.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(1,4-dioxo-3-(4-phenylpiperazin-1-yl)-1,4-dihydronaphthalen-2-yl)benzamide (C27H23N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H23N3O3 |
| Molecular Weight | 437.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-(12,14-Dioxo-9,10-dihydro-9,10-[3,4]epipyrroloanthracen-13-yl)-N-(4-methoxyphenyl)acetamide (CAS 478029-58-2)
- 4-{16,18-dioxo-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2,4,6,9(14),10,12-hexaen-17-yl}-N-(propan-2-yl)benzamide (CAS 861209-02-1)
- (2E)-2-{4-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}-3-(naphthalen-1-yl)prop-2-enenitrile (CAS 866051-09-4)
- 4-(1,3-Dioxo-2,3-dihydro-1H-inden-2-ylidene)-2-phenyl-6-(pyridin-2-yl)-octahydropyrrolo[3,4-c]pyrrole-1,3-dione (CAS 321392-06-7)
- 9,10-Dioxo-9,10-dihydroanthracene-1,2,5,8-tetrayl tetraacetate (CAS 2885-46-3)
- 2-(12,14-Dioxo-9,10-dihydro-9,10-[3,4]epipyrroloanthracen-13-yl)-4-nitrobenzoic acid (CAS 499999-52-9)
- 4-{16,18-dioxo-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2,4,6,9(14),10,12-hexaen-17-yl}-N-(prop-2-en-1-yl)benzamide (CAS 861209-03-2)
- 4-(((3,5-Dioxo-1,2-diphenylpyrazolidin-4-yl)methylene)amino)benzenesulfonamide (CAS 59541-36-5)
Recommended Standards
- Alobresib, >98% (HPLC) (CAS 1637771-14-2)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(naphthalen-1-yl)propanoic acid (CAS 176036-48-9)
- Cyclazosin (CAS 139953-73-4)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[3-(propan-2-yl)phenyl]acetamide (CAS 1775338-53-8)
- Pyrazin-2-ylmethanamineoxalate (CAS 1170817-91-0)
- (S)-2-Amino-1-(3-(benzyl(methyl)amino)piperidin-1-yl)ethanone (CAS 1354001-04-9)
- 2-Butene-1,1,1,4,4,4-d (CAS 358731-97-2)
- Bis(3,5,6-trichloro-2-n-pentyloxycarbonylphenyl) oxalate (CAS 75203-51-9)
- Ethyl 5-amino-3-methyl-1-(4-methylphenyl)-1H-pyrazole-4-carboxylate (CAS 2096986-79-5)
- Eugenol Impurity 13 (CAS 1426542-80-4)
- 5-Aminopyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 255715-66-3)
- 2-(6-ethynyl-3-pyridyl)acetic acid (CAS 1211540-18-9)
- 6-Methoxy-N-(2-(3-methylisoxazol-5-yl)ethyl)-1H-indole-2-carboxamide (CAS 1421443-68-6)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com