2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[3-(propan-2-yl)phenyl]acetamide CAS 1775338-53-8
| CAS No. | 1775338-53-8 |
| Molecular Formula | C23H27N5O4 |
| Molecular Weight | 437.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[3-(propan-2-yl)phenyl]acetamide.
CATO supplies 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[3-(propan-2-yl)phenyl]acetamide (CAS 1775338-53-8), a certified reference material (molecular formula C23H27N5O4, MW 437.49 g/mol) for analytical method development and quality control.
Structurally, 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[3-(propan-2-yl)phenyl]acetamide (C23H27N5O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 437.49 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-[3-(propan-2-yl)phenyl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27N5O4 |
| Molecular Weight | 437.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 5 |
Related Methyl Standards
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-ethylphenyl)acetamide (CAS 1775353-89-3)
- 4-[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]-1-(3,4,5-trimethoxybenzoyl)piperidine (CAS 1775399-37-5)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(3-phenylpropyl)acetamide (CAS 1775484-63-3)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(2-ethyl-6-methylphenyl)acetamide (CAS 1775502-92-5)
- 4-(5-Methyl-1,2,4-oxadiazol-3-yl)-2-{[4-(trifluoromethoxy)phenyl]methyl}-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepine-1,3-dione (CAS 1775346-21-8)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-[(4-methoxyphenyl)methyl]acetamide (CAS 1775308-30-9)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(3-methoxyphenyl)acetamide (CAS 1775386-91-8)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-methoxyphenyl)acetamide (CAS 1775402-99-7)
Recommended Standards
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(naphthalen-1-yl)propanoic acid (CAS 176036-48-9)
- N-(2,6-Dimethylphenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775345-70-4)
- N-(1,4-dioxo-3-(4-phenylpiperazin-1-yl)-1,4-dihydronaphthalen-2-yl)benzamide (CAS 1640259-27-3)
- Alobresib, >98% (HPLC) (CAS 1637771-14-2)
- (S)-2-((tert-butoxycarbonyl)amino)-3-(3,5-dichloro-4-hydroxyphenyl)propanoic acid (CAS 123418-41-7)
- 2-((Tetrahydro-2H-pyran-4-yl)oxy)ethane-1-sulfonamide (CAS 1485448-45-0)
- Ac-2-Nal-OH (CAS 37439-99-9)
- 5-Chloro-3-fluoro-2-methylpyridine (CAS 1210868-68-0)
- Methyl (2R,4R)-4-fluoropyrrolidine-2-carboxylate (CAS 1064078-37-0)
- Dapagliflozin Impurity 90 (CAS 29643-62-7)
- 6-Bromo-1-methylquinoxalin-2(1H)-one (CAS 1379154-54-7)
- 6-Amino-3-(bromomethyl)-5-(difluoromethyl)pyridin-2-ol (CAS 1804678-17-8)
- 4-(3-Methylbenzyl)thiomorpholine (CAS 414882-72-7)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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