Ticagrelor Impurity 12 (Mixture of Diastereomers) CAS 1644461-85-7
| CAS No. | 1644461-85-7 |
| Molecular Formula | C23H28F2N6O5S |
| Molecular Weight | 538.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ticagrelor Impurity 12 (Mixture of Diastereomers) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ticagrelor Impurity 12 (Mixture of Diastereomers) (CAS 1644461-85-7), a pharmacopoeial impurity reference standard (molecular formula C23H28F2N6O5S, MW 538.57 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ticagrelor Impurity 12 (Mixture of Diastereomers) (C23H28F2N6O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H28F2N6O5S |
| Molecular Weight | 538.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 108 (CAS 2417798-14-0)
- Ticagrelor Impurity 90 (CAS 2417326-48-6)
- Ticagrelor Impurity 117 (CAS CATO-C4X-1093117)
- Ticagrelor Impurity 141 (CAS CATO-C4X-1093141)
- Ticagrelor Impurity 181 (CAS CATO-C4X-1093181)
- Ticagrelor Impurity 30 (CAS CATO-C4X-109330)
- Ticagrelor Impurity 118 (CAS 2205903-72-4)
- Ticagrelor-d7 (CAS 1265911-55-4)
Recommended Standards
- N-[2-[(3aR,8aS)-3a,8a-Dihydro-8H-indeno[1,2-d]oxazol-2-yl]phenyl]-2-(diphenylphosphino)benzamide (CAS 2750202-75-4)
- Cefprozil EP Impurity H (CAS CATO-C4X-149214)
- 5-Methoxy-2-methyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl)pyrazolo[1,5-a]pyridine-3-carboxamide (CAS 1799682-71-5)
- Cefprozil EP Impurity J (CAS CATO-C4X-149215)
- Bisoprolol Impurity 52 (CAS 293302-44-0)
- Apremilast Impurity 21 (CAS CATO-C4X-100921)
- Bromhexine Hydrochloride EP Impurity E (CAS CATO-C4X-106028)
- 2,2,2-Trifluoro-1-(3-methylpyridin-2-yl)ethan-1-ol (CAS 2091531-55-2)
- Nilestrio Unknown Impurity 1 (CAS CATO-CPS-2602001)
- Ethyl 3-bromo-4-methyl-2-oxopentanoate (CAS 50774-88-4)
- 2-Cyano-N-(2-ethylphenyl)-3-(4-methoxyphenyl)propanamide (CAS 1260939-80-7)
- Methyl 2-amino-4-chloro-5-(trifluoromethyl)benzoate (CAS 1698027-36-9)
- Methylene blue /Methylthioninium Chloride Impurity 22 (CAS 34185-23-4)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com