Bisoprolol Impurity 52 CAS 293302-44-0
| CAS No. | 293302-44-0 |
| Molecular Formula | C10H13ClO3 |
| Molecular Weight | 216.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Bisoprolol Impurity 52 (CAS 293302-44-0), a pharmacopoeial impurity reference standard (molecular formula C10H13ClO3, MW 216.66 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H13ClO3, Bisoprolol Impurity 52 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 216.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13ClO3 |
| Molecular Weight | 216.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Bisoprolol Standards
- Bisoprolol Impurity 51 (CAS 62911-12-0)
- Bisoprolol Impurity 102 (CAS CATO-C4X-1247102)
- Bisoprolol Impurity 14 (CAS 177034-57-0)
- Bisoprolol Impurity 79 (CAS 1039828-27-7)
- Bisoprolol EP Impurity R (CAS 5790-46-5)
- Bisoprolol Impurity 101 (CAS CATO-C4X-1247101)
- Bisoprolol Impurity 83 (CAS CATO-C4X-124783)
- Bisoprolol Impurity 82 (CAS 313975-07-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com